https:\/\/pubmed.ncbi.nlm.nih.gov\/22712832\/<\/a><\/p>\nThis study describes patient adherence to leukemia maintenance therapy and the factors associated with nonadherence, with a particular focus on the different age groups concerned. Sixty-four in-depth interviews were performed in three centers among 31 parents of children, 12 parents of adolescents, 12 adolescents, and 9 adult patients. Adherence was determined through a multimethod approach based on patient and\/or parent responses to three self-administered questions and patient and\/or parent interviews.<\/p>\n
The results were compared with physician evaluation of adherence. Factors explaining nonadherence were investigated in the in-depth interviews and by statistical analysis of self-administered questionnaires. Intentional nonadherence occurred rarely (4\/52 patients, 8%) following poor tolerance of the maintenance therapy. Despite a high motivation to follow the maintenance therapy, repeated forgetfulness (8\/52, 15%) was not rare and rarely detected by physicians.<\/p>\n
Nonadherence increased with age, but also existed among children. Outings, the administration of therapy at bedtime, the lack of monitoring, a low socioeconomic status, and the hepatic side effects of the treatment were also associated with nonadherence.<\/p>\n
Declared nonadherence of leukemia maintenance therapy is not negligible and should be screened at follow-up consultations using three simple questions.<\/p>\n","protected":false},"excerpt":{"rendered":"
Julien Mancini, Marie-Claude Simeoni, Nathalie Parola, Audrey Clement, Norbert Vey, Nicolas Sirvent, G\u00e9rard Michel and Pascal Auquier. Pediatr Hematol Oncol.\u00a02012 […]<\/p>\n","protected":false},"template":"","keywords":[41,39],"class_list":["post-296","publications_science","type-publications_science","status-publish","hentry","keywords-leukemia-maintenance-therapy","keywords-nonadherence-in-hematological-malignancies"],"acf":[],"yoast_head":"\n
8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults. - Lea<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults. - Lea\" \/>\n<meta property=\"og:description\" content=\"Julien Mancini, Marie-Claude Simeoni, Nathalie Parola, Audrey Clement, Norbert Vey, Nicolas Sirvent, G\u00e9rard Michel and Pascal Auquier. Pediatr Hematol Oncol.\u00a02012 […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/\" \/>\n<meta property=\"og:site_name\" content=\"Lea\" \/>\n<meta property=\"article:modified_time\" content=\"2021-03-02T14:13:12+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":[\"WebPage\",\"MedicalWebPage\"],\"@id\":\"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/\",\"url\":\"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/\",\"name\":\"8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults. - Lea\",\"isPartOf\":{\"@id\":\"https:\/\/plateforme-lea.fr\/en\/#website\"},\"datePublished\":\"2012-04-02T18:48:17+00:00\",\"dateModified\":\"2021-03-02T14:13:12+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/plateforme-lea.fr\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Scientific publications\",\"item\":\"https:\/\/plateforme-lea.fr\/en\/publications_science\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/plateforme-lea.fr\/en\/#website\",\"url\":\"https:\/\/plateforme-lea.fr\/en\/\",\"name\":\"Lea\",\"description\":\"Malignant haemopathies in children and adolescents\",\"publisher\":{\"@id\":\"https:\/\/plateforme-lea.fr\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/plateforme-lea.fr\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/plateforme-lea.fr\/en\/#organization\",\"name\":\"Plateforme LEA\",\"url\":\"https:\/\/plateforme-lea.fr\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/plateforme-lea.fr\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/plateforme-lea.fr\/wp-content\/uploads\/2020\/12\/cropped-lea-logotype.png\",\"contentUrl\":\"https:\/\/plateforme-lea.fr\/wp-content\/uploads\/2020\/12\/cropped-lea-logotype.png\",\"width\":600,\"height\":260,\"caption\":\"Plateforme LEA\"},\"image\":{\"@id\":\"https:\/\/plateforme-lea.fr\/en\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults. - Lea","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/","og_locale":"en_US","og_type":"article","og_title":"8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults. - Lea","og_description":"Julien Mancini, Marie-Claude Simeoni, Nathalie Parola, Audrey Clement, Norbert Vey, Nicolas Sirvent, G\u00e9rard Michel and Pascal Auquier. Pediatr Hematol Oncol.\u00a02012 […]","og_url":"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/","og_site_name":"Lea","article_modified_time":"2021-03-02T14:13:12+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":["WebPage","MedicalWebPage"],"@id":"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/","url":"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/","name":"8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults. - Lea","isPartOf":{"@id":"https:\/\/plateforme-lea.fr\/en\/#website"},"datePublished":"2012-04-02T18:48:17+00:00","dateModified":"2021-03-02T14:13:12+00:00","breadcrumb":{"@id":"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/plateforme-lea.fr\/en\/publications_science\/adherence-to-leukemia-maintenance-therapy-a-comparative-study-among-children-adolescents-and-adults\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/plateforme-lea.fr\/en\/"},{"@type":"ListItem","position":2,"name":"Scientific publications","item":"https:\/\/plateforme-lea.fr\/en\/publications_science\/"},{"@type":"ListItem","position":3,"name":"8. Adherence to Leukemia Maintenance Therapy: A Comparative Study Among Children, Adolescents, and Adults."}]},{"@type":"WebSite","@id":"https:\/\/plateforme-lea.fr\/en\/#website","url":"https:\/\/plateforme-lea.fr\/en\/","name":"Lea","description":"Malignant haemopathies in children and adolescents","publisher":{"@id":"https:\/\/plateforme-lea.fr\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/plateforme-lea.fr\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/plateforme-lea.fr\/en\/#organization","name":"Plateforme LEA","url":"https:\/\/plateforme-lea.fr\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/plateforme-lea.fr\/en\/#\/schema\/logo\/image\/","url":"https:\/\/plateforme-lea.fr\/wp-content\/uploads\/2020\/12\/cropped-lea-logotype.png","contentUrl":"https:\/\/plateforme-lea.fr\/wp-content\/uploads\/2020\/12\/cropped-lea-logotype.png","width":600,"height":260,"caption":"Plateforme LEA"},"image":{"@id":"https:\/\/plateforme-lea.fr\/en\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/plateforme-lea.fr\/en\/wp-json\/wp\/v2\/publications_science\/296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/plateforme-lea.fr\/en\/wp-json\/wp\/v2\/publications_science"}],"about":[{"href":"https:\/\/plateforme-lea.fr\/en\/wp-json\/wp\/v2\/types\/publications_science"}],"version-history":[{"count":0,"href":"https:\/\/plateforme-lea.fr\/en\/wp-json\/wp\/v2\/publications_science\/296\/revisions"}],"wp:attachment":[{"href":"https:\/\/plateforme-lea.fr\/en\/wp-json\/wp\/v2\/media?parent=296"}],"wp:term":[{"taxonomy":"keywords","embeddable":true,"href":"https:\/\/plateforme-lea.fr\/en\/wp-json\/wp\/v2\/keywords?post=296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}